Switching to Another SSRI or to Venlafaxine With or Without Cognitive Behavioral Therapy for Adolescents With SSRI-Resistant Depression
نویسندگان
چکیده
منابع مشابه
Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trial.
CONTEXT Only about 60% of adolescents with depression will show an adequate clinical response to an initial treatment trial with a selective serotonin reuptake inhibitor (SSRI). There are no data to guide clinicians on subsequent treatment strategy. OBJECTIVE To evaluate the relative efficacy of 4 treatment strategies in adolescents who continued to have depression despite adequate initial tr...
متن کاملL-methylfolate Plus SSRI or SNRI from Treatment Initiation Compared to SSRI or SNRI Monotherapy in a Major Depressive Episode.
OBJECTIVE Evaluate the efficacy of L-methylfolate in combination with SSRI or SNRI compared to SSRI or SNRI monotherapy in a major depressive episode. DESIGN A retrospective analysis of L-methylfolate plus SSRI/SNRI at treatment initiation (n=95) and SSRI/SNRI monotherapy (n=147) from patient charts. SETTING Outpatient, private psychiatric clinic/practice. PARTICIPANTS Adults 18 to 70 wit...
متن کاملPharmacy and medical costs associated with switching between venlafaxine and SSRI antidepressant therapy for the treatment of major depressive disorder.
BACKGROUND While much has been published on utilization of antidepressants and associated resource use, surprisingly little information is available on the relationship between a change in antidepressant agent and health care utilization. Given that many patients will not respond to initial therapy (and therefore would be candidates for switching treatment) and the array of antidepressant medic...
متن کاملSSRI OR serotonin reuptake inhibitor OR tricyclic antidepressant; drug-induced akathisia; SSRI AND early onset OR psychomotor agitation OR aggression OR hostility OR impulsivity; and TCA/ tricyclic OR SSRI
in anxiety, agitation and irritability. Medical literature and guidelines cite this phenomenon, advising caution when prescribing selective serotonin reuptake inhibitors (SSRIs), especially for anxiety disorders. This phenomena is also used to support theoretical hypotheses of antidepressant action. However, we believe it remains inconsistently and poorly defined. For consistency in this system...
متن کاملComputer-Based Cognitive Behavioral Therapy for Anxiety Disorders or Depression
technology and target group Anxiety and depression are two conditions that affect a large percentage of the population. Anxiety refers to an intensive sense of apprehension and distress associated with anticipated danger or harm. The symptoms are distinguished by having both physical and psychological characteristics. Anxiety disorders refer to multiple anxiety symptoms that present concurrentl...
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ژورنال
عنوان ژورنال: JAMA
سال: 2008
ISSN: 0098-7484
DOI: 10.1001/jama.299.8.901